Latest steps in escort aptamer thinking include artificial modifications of one’s truncated aptamer

Latest steps in escort aptamer thinking include artificial modifications of one's truncated aptamer Further nuclease stabilization is achieved by substitution of 2?-OCHstep 3 for 2?-OH at purine positions. As the 2?-OCH3 moiety is not compatible with current SELEX process enzymes, this alteration must occur during chemical...